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5-APB

5-(2-Aminopropyl)benzofuran (commonly known as 5-APB) is a lesser-known entactogen of the benzofuran class that produces MDA-like entactogenic and stimulating effects when administered. It is structurally related to entactogens like 5-MAPB, 6-APB, and MDA.

Compared to other members of its family such as 6-APB and 5-MAPB, this compound in particular is known for its stimulating and euphoric effects which has resulted in its rise in popularity as a product which is easily accessible through the use of online research chemical vendors. It has been commercially distributed as a designer drug alternative to MDMA since 2010.

5-(2-aminopropyl)benzofuran, also known as 5-APB, is a benzofuran and phenethylamine, meaning it has an ethylamine chain and a furan ring attached to the core benzene ring. It can also be classified as an amphetamine derivative because the ethylamine chain is alpha methylated.

5-APB is a triple reuptake inhibitor for norepinephrine, dopamine and serotonin as well as being an agonist for the 5-HT2A and 5-HT2B receptors. It has also been speculated that 5-APB acts as a releasing agent for the previously mentioned neurotransmitters.

This means it effectively boosts the levels of the serotonin, norepinephrine and dopamine neurotransmitters in the brain by binding to and partially blocking the transporter proteins that normally remove those monoamines from the synaptic cleft. This allows dopamine and norepinephrine to accumulate within the brain, resulting in stimulating and euphoric effects.

Physical effects
Stimulation
Abnormal heartbeat
Increased heart rate
Muscle contractions
Increased perspiration
Dehydration
Appetite suppression
Nausea
Temporary erectile dysfunction

5-APB is sold for research purposes only and is not be utilized for any other purposes.

5-MAPB

5-(2-methylaminopropyl)benzofuran (abbreviated 5-MAPB) is a synthetic entactogen of the substituted benzofuran class of chemicals, which are known to produce euphoric, entactogenic, stimulating and mildly hallucinogenic effects. These include such MDA-inspired substances as 5-APB, 6-APB and 5-EAPB, among others. 5-MAPB is the N-methylated form of 5-APB, analogously to how MDMA is the N-methylated form of MDA.

5-MAPB is commonly found as the succinate and hydrochloride salt. The hydrochloride salt is 10% more potent by mass so doses should be adjusted accordingly.

5-(2-methylaminopropyl)benzofuran, or 5-MAPB, is a substituted benzofuran and phenethylamine. It is comprised of an N-methylated ethylamine chain and a furan ring attached to a central benzene ring.

5-MAPB is a triple reuptake inhibitor for the monoamines norepinephrine, dopamine and serotonin as well as being an agonist for the 5-HT2A and 5-HT2B receptors.It has also been speculated that 5-MAPB acts as a releasing agent for the previously mentioned neurotransmitters.

Physical effects
Stimulation
Increased heart rate
Dehydration
Appetite suppression
Nausea
Temporary erectile dysfunction
Increased perspiration

Visual effects
Acuity enhancement

5-MAPB is sold for research purposes only and is not be utilized for any other purposes.

6-APB (New)

6-(2-Aminopropyl)benzofuran (also known as 6-APB and “Benzofury“) is a entactogen substance of the benzofuran class. Its characteristic effects include anxiety suppression, disinhibition, muscle relaxation, and euphoria. It is structurally related to entactogens like MDA,MDMA,5-APB, and 5-MAPB.

6-APB, also known as 6-(2-aminopropyl)benzofuran, is a synthetic molecule of the benzofuran class. The benzofuran class of substances are members of the amphetamine and phenylethylamine classes. Molecules of this class contain a phenethylamine core bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. 6-APB does not contain a methyl substitution on RN. It is composed of an an oxygen-substituted benzofuran ring fused at R3 and R4 of the phenyl ring.

Notably, 6-APB shares this benzofuran ring with related compounds such as 5-APB, 5-MAPB, and 6-MAPB.

6-APB is a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) with Ki values of 117, 150, and 2698 nM for the norepinephrine transporter (NET), dopamine transporter (DAT), and serotonin transporter (SERT), respectively.6-APB also possesses additional activity as a releasing agent of these monoamine neurotransmitters.

Physical effects
Stimulation & Sedation
Spontaneous physical sensations
Tactile enhancement
Bodily control enhancement
Stamina enhancement
Temperature regulation suppression
Increased bodily temperature
Vibrating vision

5-MeO-DiBF is sold for research purposes only and is not be utilized for any other purposes.