5F-PB225F-PB-22 (1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester) is a synthetic cannabinoid and agonist of the cannabinoid receptors which produces predominantly sedating subjective effects somewhat similar to that of cannabis.Cannabinoids are commonly smoked or vaporized to achieve a quick onset of effects and rapid offset. 5F-PB-22 is orally active when dissolved in a lipid, which can increase the duration significantly. Like other cannabinoids, it is insoluble in water but dissolves in ethanol and lipids.Physical effects Spontaneous physical sensations – The “body high” of 5F-PB-22 can be described as a warm and soft pleasurable, all-encompassing tingling sensation that spreads over the body. It maintains a consistent presence that quickly rises with the onset and hits its limit once the peak has been reached before immediately dissipating. Sedation – Generally, the effects on the user’s energy levels are very sedating. This encourages one to relax, lie down, and (at higher doses) fall asleep. It produces strong sedative effects that can be described as on par with JWH-018 and more sedating when compared to THC, JWH-073, THJ-018, AM-2201, or 5F-UR-144 but less than that of 5F-AKB48. Motor control loss Appetite enhancement Dehydration Vasodilation Pain relief Perception of bodily heaviness or Perception of bodily lightness Changes in gravity5F-PB-22 is sold for research purposes only and is not be utilized for any other purposes.