3,4-Methylenedioxyamphetamine (MDA), is an empathogen-entactogen, psychostimulant, and psychedelic drug of the amphetamine family that is encountered mainly as a recreational drug. In terms of pharmacology, MDA acts most importantly as a serotonin-norepinephrine-dopamine releasing agent (SNDRA). Due to its euphoriant and hallucinogenic effects.
MDA is rarely sought after as a recreational drug compared to other drugs in the amphetamine family, however it remains an important and widely used drug due to it being a primary metabolite,the product of hepatic N-dealkylation,of MDMA (ecstasy), In addition, it is not uncommon to find MDA as an adulterant of illicitly produced MDMA.
MDA is a substrate of the serotonin, norepinephrine, dopamine, and vesicular monoamine transporters, as well as a TAAR1 agonist,and for these reasons acts as a reuptake inhibitor and releasing agent of serotonin, norepinephrine, and dopamine
The (S)-optical isomer of MDA is more potent than the (R)-optical isomer as a psychostimulant, possessing greater affinity for the three monoamine transporters.
In terms of the subjective and behavioral effects of MDA, it is thought that serotonin release is required for its empathogen-entactogen effects, release of dopamine and norepinephrine is responsible for its psychostimulant effects, dopamine release is necessary for its euphoriant (rewarding and addictive) effects, and direct agonism of the serotonin 5-HT2A receptor is causative of its psychedelic effects.
3-4-MD-A-PBP is sold for research purposes only and is not be utilized for any other purposes.