(12 customer reviews)

AM-1220 is a drug that acts as a potent and moderately selective agonist for the cannabinoid receptor CB1, with around 19x selectivity for CB1 over the related CB2 receptor.

The (piperidin-2-yl)methyl side chain of AM-1220 contains a stereocenter, so there are two enantiomers with quite different potency, the (R) enantiomer having a Ki of 0.27nM at CB1 while the (S) enantiomer has a much weaker Ki of 217nM.

A number of related compounds are known with similar potent cannabinoid activity, with modifications such as substitution of the indole ring at the 2- or 6- positions, the naphthoyl ring substituted at the 4- position or replaced by substituted benzoyl rings or other groups, or the 1-(N-methylpiperidin-2-ylmethyl) group replaced by similar heterocyclic groups such as N-methylpyrrolidin-2-ylmethyl or N-methylmorpholin-3-ylmethyl.AM-1220 was first detected as an ingredient of synthetic cannabis smoking blends in 2010

AM-1220 is sold for research purposes only and is not be utilized for any other purposes.

12 reviews for AM-1220

  1. Jules

    Je suis très satisfait des résultats obtenus jusqu’à présent avec le «AM-2201″ que j’ai acheté.
    Expédition très efficace, livraison plus rapide que prévue. La qualité était quoi
    J’attendais avec impatience et cet “” AM-2201 “ne m’a pas déçu.
    Tous mes amis qui y ont goûté ont vraiment apprécié.
    Nous passerions une autre commande bientôt.

  2. Stacey

    So happy with the results, this is just too good to be true , paying with bitcoin and got such a high quality chemical .

    Much appreciated .


  3. Ethan

    I will be making more order soon , was really grateful with my products . They are of high quality.


  4. Henry

    One of my favorite products and very pleased with the quality .


  5. Lee

    This is my 3rd order here , all of great quality . I really do respect this store .


  6. Ashley

    This is a great store , they got quality products and free and fast delivery, is hard to see such stores today online. They also accept bitcoin as payment means.


  7. Cliff

    I am very satisfied with the results obtained so far with the “AM-2201” I bought.
    Very efficient shipping, delivery faster than expected. Quality was what
    I was waiting impatiently and this “” AM-2201 “did not disappoint me.
    All my friends who have tasted it really appreciated.
    We would place another order soon.
    Thank you


  8. Josep

    Je vais bientôt faire plus de commande, était vraiment reconnaissant avec mes produits. Ils sont de grande qualité.


  9. Henry

    La AM-1220 obtenue dans ce magasin est vraiment de grande qualité.
    C’est un magasin de confiance, j’ai des preuves.
    tellement heureux de la qualité. C’est le meilleur AM-1220, que j’ai jamais acheté.


  10. WRIGHT

    I really do enjoy this product and especially when i get from this online vendor , is one of the best and they are just too good . I will be making more order again soon and hope getting same quality .


  11. Larry

    Thanks for the AM-1220 , was really nice making payment with bitcoin.


  12. Melvin

    Customer service is fantastic. Responses to anything at all are usually super quick and, above all, helpful. If you have any hesitation about a new RC company, don’t worry. You’ll have a great experience with I couldn’t be happier with the order process. I had to reach out and just say how great that the team here is.



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